Fenbendazole For Cancer
Fenbendazole is an anti-helminth drug used to treat parasitic worms. It was found to have a possible suppressive effect on cancer cells in a mouse study, but there is no sufficient evidence that it will help human patients. It’s not approved as a cancer treatment in Korea, so there aren’t many patients who know it exists. But it’s gaining popularity in the US and elsewhere after a man with lung cancer claimed that fenbendazole and other supplements cured him. It appears that the drug acts by stopping the growth of microtubules, which provide structure to all cells and a highway for transporting nutrients.
The first place through which participants heard about fenbendazole was TV, and then the Internet, especially portal sites and YouTube. It was also said that acquaintances or family members gave the information, although this was less common than when it came from the media.
Participants were interviewed using a semi-structured questionnaire containing three categories: the acquisition channel of general cancer information and false information about fenbendazole, the quality of the obtained information, and perceptions toward this information. The results showed that the majority of patients were confused about the effects and safety of fenbendazole, and they had an insufficient understanding of its mechanism of action. In addition, the findings showed that fenbendazole induced ferroptosis in both SNU-C5 and SNU-C5/5-FUR colorectal cancer cells. This process is mediated by the inactivation of cysteine uptake by SLC7A11 and decreased expression of the lipid repair enzyme GPX4. The effects of anti-ferroptotic agents were analyzed to establish that ferroptosis was the main cell death pathway in fenbendazole treatment. fenbendazole for cancer